The meeting "Hedgehog Signalling in Development Evolution and Disease" will be held March 18-21， 2012 at Biopolis in Singapore.

Hedgehog (HH) proteins constitute one of a small number of families of secreted signals that play a central role in the development of metazoans. First discovered in Drosophila， research over the past 15 years has unveiled the key role played by HH signaling in human development and disease: aberrant HH signaling is now recognized as being associated with around 25% of all human cancers.

The meeting will reflect the many facets of HH signaling， with sessions devoted to the mechanisms of signal transduction， the developmental roles of HH， the evolutionary origins of the pathway， its involvement in human diseases and its importance as a therapeutic target， providing a well rounded and comprehensive survey of the field.

Deadline for abstract submission and early bird registration is December 31， 2011.
Deadline for normal registration is January 31， 2011.